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1 Strip = 4 Capsules
Incepta Pharmaceuticals Ltd.Product Description
Cefixime Trihydrate is an orally active, third-generation cephalosporin antibiotic characterized by its broad spectrum of activity against a variety of Gram-negative and certain Gram-positive bacteria. It exerts its bactericidal effect by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, which inhibits the final transpeptidation step of peptidoglycan synthesis, ultimately leading to osmotic instability and cell lysis. Notably, Cefixime exhibits high stability in the presence of many beta-lactamase enzymes, making it effective against organisms that are resistant to penicillins and earlier cephalosporins. It is frequently indicated for the treatment of uncomplicated urinary tract infections, respiratory tract infections such as bronchitis and pharyngitis, and otitis media. From a pharmacokinetic perspective, Cefixime is distinguished by a relatively long elimination half-life compared to other oral cephalosporins, allowing for convenient once- or twice-daily dosing. While generally well-tolerated, its use requires clinical oversight to prevent the development of antimicrobial resistance and to monitor for common gastrointestinal side effects or rare hypersensitivity reactions.
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